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Literature summary extracted from

  • Webb, L.J.; Miles, K.K.; Auyeung, D.J.; Kessler, F.K.; Ritter, J.K.
    Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8 (2005), Drug Metab. Dispos., 33, 77-82.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.17 expression in HEK cells Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus P70624
-
-
2.4.1.17 Rattus norvegicus Q64634
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 intestine high expression Rattus norvegicus
-
2.4.1.17 kidney
-
 Rattus norvegicus
-
2.4.1.17 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-1-yl-beta-D-glucuronide
-
 ?
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Rattus norvegicus UDP + naphth-1-yl-beta-D-glucuronide
-
 ?
2.4.1.17 10-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-10-yl-beta-D-glucuronide
-
 ?
2.4.1.17 11-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-11-yl-beta-D-glucuronide
-
 ?
2.4.1.17 12-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-12-yl-beta-D-glucuronide
-
 ?
2.4.1.17 17beta-estradiol + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 17beta-ethynylestradiol + UDPglucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 2-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-2-yl-beta-D-glucuronide
-
 ?
2.4.1.17 3,5-dinitrocatechol + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 3-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-3-yl-beta-D-glucuronide
-
 ?
2.4.1.17 4-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-4-yl-beta-D-glucuronide
-
 ?
2.4.1.17 4-hydroxybiphenyl + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-methylumbelliferone + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 5-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-5-yl-beta-D-glucuronide
-
 ?
2.4.1.17 6-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-6-yl-beta-D-glucuronide
-
 ?
2.4.1.17 7-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-7-yl-beta-D-glucuronide
-
 ?
2.4.1.17 7-hydroxycoumarin + UDP-glucuronate
-
 Rattus norvegicus UDP + coumarin-7-yl-alpha-D-glucuronide
-
 ?
2.4.1.17 8-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-8-yl-beta-D-glucuronide
-
 ?
2.4.1.17 9-hydroxybenzo[a]pyrene + UDP-glucuronate
-
 Rattus norvegicus UDP + benzo[a]pyren-9-yl-beta-D-glucuronide
-
 ?
2.4.1.17 benzo[a]pyrene-7,8(+)-diol + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 benzo[a]pyrene-7,8(-)diol + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 bisphenol A + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 chrysin + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 epicatechin + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 estriol + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 estrone + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?
2.4.1.17 propofol + UDP-glucuronate
-
 Rattus norvegicus UDP + propofyl beta-D-glucuronide
-
 ?
2.4.1.17 serotonin + UDP-glucuronate
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.17 UGT1A7
-
 Rattus norvegicus
2.4.1.17 UGT1A8
-
 Rattus norvegicus