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Literature summary extracted from

  • Nishiyama, T.; Ogura, K.; Nakano, H.; Kaku, T.; Takahashi, E.; Ohkubo, Y.; Sekine, K.; Hiratsuka, A.; Kadota, S.; Watabe, T.
    Sulfation of environmental estrogens by cytosolic human sulfotransferases (2002), Drug Metab. Pharmacokinet., 17, 221-228.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.2
-
 Homo sapiens
2.8.2.2 SULT2A1 bacterially expressed as His tagged protein in Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.2 0.002
-
 dehydroepiandrosterone pH 7.4, 37°C Homo sapiens
2.8.2.2 0.0043
-
 4,4'-isopropylidenediphenol pH 7.4, 37°C Homo sapiens
2.8.2.2 0.0051
-
 4-(1,1,3,3-tetramethylbutyl)phenol pH 7.4, 37°C Homo sapiens
2.8.2.2 0.041
-
 genistein pH 7.4, 37°C Homo sapiens
2.8.2.2 0.0715
-
 4-n-nonylphenol pH 7.4, 37°C Homo sapiens
2.8.2.2 0.1673
-
 daidzein pH 7.4, 37°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.2 cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.2 35930
-
 calculated from putative amino acid sequence, estimated from cDNA Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.2 Homo sapiens
-
 human
-
2.8.2.2 Homo sapiens Q06520 human, SULT2A1, cDNA
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.2 3'-phosphoadenylylsulfate + 4,4'-isopropylidenediphenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + 4-(1,1,3,3-tetramethylbutyl)phenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-(1,1,3,3-tetramethylbutyl)phenyl sulfate
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + 4-n-nonylphenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-n-nonylphenyl sulfate
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + daidzein
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.2 3'-phosphoadenylylsulfate + genistein
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.2 SULT2A1 previously DHEA-ST Homo sapiens