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Literature summary extracted from

  • Suiko, M.; Sakakibara, Y.; Liu, M.C.
    Sulfation of environmental estrogen-like chemicals by human cytosolic sulfotransferases (2000), Biochem. Biophys. Res. Commun., 267, 80-84.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.1 cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.1 3'-phosphoadenylylsulfate + a phenol Homo sapiens sulfation of environmental estrogens, overview adenosine 3',5'-bisphosphate + an aryl sulfate
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Homo sapiens
-
SULT1C1 and SULT1C2
-
2.8.2.1 Homo sapiens
-
2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.1 Hep-G2 cell hepatoma cell line Homo sapiens
-
2.8.2.1 hepatoma cell
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.1 0.0000007
-
purified SULT1C1, substrate 4-nitrophenol Homo sapiens
2.8.2.1 0.0019
-
purified SULT1C2, substrate 4-octylphenol Homo sapiens
2.8.2.1 0.002
-
purified P-PST, substrate 4-nonylphenol Homo sapiens
2.8.2.1 0.0028
-
purified M-PST, substrate dopamine Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + a phenol
-
Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol M-PST Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol P-PST Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol SULT1C1: specific for Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol SULT1C2 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nonylphenol P-PST, M-PST, SULT1C2, not SULT1C1 Homo sapiens adenosine 3',5'-bisphosphate + 4-nonylphenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nonylphenol P-PST: best substrate Homo sapiens adenosine 3',5'-bisphosphate + 4-nonylphenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-octylphenol SULT1C2: best substrate Homo sapiens adenosine 3',5'-bisphosphate + 4-octylphenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + 4-octylphenol P-PST, M-PST, SULT1C2, not SULT1C1 Homo sapiens adenosine 3',5'-bisphosphate + 4-octylphenyl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + a phenol sulfation of environmental estrogens, overview Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
?
2.8.2.1 3'-phosphoadenylylsulfate + bisphenol A P-PST, M-PST, SULT1C2, not SULT1C1 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.1 3'-phosphoadenylylsulfate + dopamine M-PST: best substrate Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.1 3'-phosphoadenylylsulfate + dopamine P-PST Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.1 additional information substrate specificity Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.1 SULT
-
Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.1 37
-
assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.1 7
-
assay at Homo sapiens