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Literature summary extracted from

  • Krenitsky, T.A.; Spector, T.; Hall, W.W.
    Xanthine oxidase from human liver: purification and characterization (1986), Arch. Biochem. Biophys., 247, 108-119.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.17.3.2 additional information
-
additional information
-
Homo sapiens
1.17.3.2 0.004
-
allopurinol
-
Homo sapiens
1.17.3.2 0.55
-
formycin B
-
Homo sapiens
1.17.3.2 0.93
-
benzaldehyde
-
Homo sapiens
1.17.3.2 48
-
N-methylnicotinamide
-
Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.3.2 Iron iron-molybdenum protein Homo sapiens
1.17.3.2 Molybdenum an iron-molybdenum protein Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.17.3.2 150000
-
2 * 150000, SDS-PAGE Homo sapiens
1.17.3.2 300000
-
gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.17.3.2 additional information
-
Homo sapiens
1.17.3.2 proteolytic modification
-
Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
1.17.3.2
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 liver
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.17.3.2 1.8
-
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 adenine + H2O + O2
-
Homo sapiens 6-amino-7,9-dihydropurin-8-one + H2O2
-
?
1.17.3.2 allopurinol + H2O + O2
-
Homo sapiens ?
-
?
1.17.3.2 benzaldehyde + H2O + O2
-
Homo sapiens benzoate + H2O2
-
?
1.17.3.2 formycin B + H2O + O2
-
Homo sapiens ?
-
?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
Homo sapiens urate + 2 H2O2
-
?
1.17.3.2 N-methylnicotinamide + H2O + O2 poor oxidation reaction Homo sapiens ?
-
r
1.17.3.2 N1-methylnicotinamide + H2O + O2
-
Homo sapiens ?
-
?
1.17.3.2 purine + H2O + O2 purine and derivatives Homo sapiens 7,9-dihydropurin-8-one + H2O2
-
?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Homo sapiens uric acid + H2O2
-
?

Subunits

EC Number Subunits Comment Organism
1.17.3.2 dimer 2 * 150000, SDS-PAGE Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.3.2 FAD flavoprotein Homo sapiens