EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.4 | 4,6-dihydroxy-5-nitropyrimidine | 0.1 mM, competitive | Homo sapiens | |
2.4.2.4 | 5-Bromouracil | 0.1 mM, competitive | Homo sapiens | |
2.4.2.4 | 5-fluorouracil | 0.1 mM, competitive | Homo sapiens | |
2.4.2.4 | 5-Nitrouracil | 0.1 mM, competitive | Homo sapiens | |
2.4.2.4 | 6-aminouracil | 0.1 mM, competitive | Homo sapiens | |
2.4.2.4 | 6-benzyl-2-thiouracil | 0.1 mM, mixed inhibition | Homo sapiens | |
2.4.2.4 | allyloxymethylthymine | 0.1 mM, uncompetitive | Homo sapiens | |
2.4.2.4 | Uracil | inhibits activity in turmor tissue, but not in normal tissue | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.4 | 0.65 | - |
thymidine | normal tissue | Homo sapiens | |
2.4.2.4 | 9.3 | - |
thymidine | tumor tissue | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.4 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.4 | partial | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.4 | uterus | normal and tumor tissue | Homo sapiens | - |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.4 | 0.0011 | - |
5-Bromouracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.0051 | - |
5-Nitrouracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.006 | - |
5-Bromouracil | normal tissue | Homo sapiens | |
2.4.2.4 | 0.021 | - |
4,6-dihydroxy-5-nitropyrimidine | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.0253 | - |
5-Nitrouracil | normal tissue | Homo sapiens | |
2.4.2.4 | 0.043 | - |
5-fluorouracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.0728 | - |
5-fluorouracil | normal tissue | Homo sapiens | |
2.4.2.4 | 0.075 | - |
6-benzyl-2-thiouracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.088 | - |
6-aminouracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.127 | - |
allyloxymethylthymine | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.1286 | - |
allyloxymethylthymine | normal tissue | Homo sapiens | |
2.4.2.4 | 0.13 | - |
6-aminouracil | normal tissue | Homo sapiens | |
2.4.2.4 | 0.137 | - |
6-benzyl-2-thiouracil | normal tissue | Homo sapiens | |
2.4.2.4 | 0.158 | - |
Uracil | tumor tissue | Homo sapiens | |
2.4.2.4 | 0.211 | - |
4,6-dihydroxy-5-nitropyrimidine | normal tissue | Homo sapiens |