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Literature summary extracted from
- Purification and some properties of taurine dehydrogenase from a bacterium (1973), J. Biochem., 73, 1269-1278.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 1.4.99.2 | Stable to freeze-thawing | Bacteria |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.4.99.2 | 2-heptyl-4-hydroxyquinoline N-oxide | some inhibition | Bacteria |  |
| 1.4.99.2 | Atebrin | some inhibition | Bacteria | |
| 1.4.99.2 | Isonicotinic acid 2-isopropylhydrazine | strong inhibition | Bacteria | |
| 1.4.99.2 | methylene blue | some inhibition | Bacteria | |
| 1.4.99.2 | Neocuproine | some inhibition | Bacteria | |
| 1.4.99.2 | p-chloromercuribenzoate | strong inhibition | Bacteria | |
| 1.4.99.2 | Phenelzine | strong inhibition | Bacteria | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.4.99.2 | 0.056 | - |
phenazine methosulfate | - |
Bacteria | |
| 1.4.99.2 | 20 | - |
taurine | - |
Bacteria | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.4.99.2 | membrane | - |
Bacteria | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.4.99.2 | taurine + H2O + acceptor | Bacteria | acts only with phenazine methosulfate as electron acceptor | sulfoacetaldehyde + NH3 + reduced acceptor | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.4.99.2 | Bacteria | - |
gram-negative | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.4.99.2 | homogenous, precipitation, chromatography steps | Bacteria |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.4.99.2 | cell culture | - |
Bacteria | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.4.99.2 | 0.48 | - |
- |
Bacteria |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.4.99.2 | -20°C, 1.5 mg protein per ml, 1 month | Bacteria |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.4.99.2 | hypotaurine + H2O + phenazine methosulfate | poor substrate | Bacteria | ? + NH3 + reduced phenazine methosulfate | - |
? | |
| 1.4.99.2 | taurine + H2O + acceptor | acts only with phenazine methosulfate as electron acceptor | Bacteria | sulfoacetaldehyde + NH3 + reduced acceptor | - |
? | |
| 1.4.99.2 | taurine + H2O + phenazine methosulfate | only acts with phenazine methosulfate as electron acceptor | Bacteria | sulfoacetaldehyde + NH3 + reduced phenazine methosulfate | - |
? | |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.4.99.2 | 40 | - |
40% loss of activity in 20 min | Bacteria |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.4.99.2 | 8.4 | - |
- |
Bacteria |
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Release 2023.1 (January 2023)
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