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Literature summary extracted from

  • Youdim, M.B.H.; Tenne, M.
    Assay and purification of liver monoamine oxidase (1987), Methods Enzymol., 142, 617-627.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 additional information overview: selective inhibitors of form A and B Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.4 RCH2NH2 + H2O + O2 Rattus norvegicus responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines RCHO + NH3 + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.4
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.4 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 2-phenylethylamine + H2O + O2 MAO-B selective substrate Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
 ?
1.4.3.4 benzylamine + H2O + O2 MAO-B selective substrate Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 kynuramine + H2O + O2 nonselective substrate Rattus norvegicus 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
 ?
1.4.3.4 RCH2NH2 + H2O + O2 specificity Rattus norvegicus RCHO + NH3 + H2O2
-
 ?
1.4.3.4 RCH2NH2 + H2O + O2 responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines Rattus norvegicus RCHO + NH3 + H2O2
-
 ?
1.4.3.4 tyramine + H2O + O2 nonselective substrate Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 More isoforms differ in inhibitor sensitivity Rattus norvegicus
1.4.3.4 More MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.4 flavin flavoprotein Rattus norvegicus
1.4.3.4 flavin FAD covalently attached to each subunit of the apoprotein Rattus norvegicus