Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Baylin, S.B.; Margolis, S.
    Purification of histaminase (diamine oxidase) from human pregnancy plasma by affinity chromatography (1975), Biochim. Biophys. Acta, 397, 294-306.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.22 aminoguanidine 0.02 mM, complete inhibition, oxidation of histamine Homo sapiens
1.4.3.22 Iproniazid 0.1 mM, 68% inhibition Homo sapiens
1.4.3.22 NaCl 200 mM, approx. 50% inhibition, almost complete inhibition of the purified enzyme with 1 M NaCl Homo sapiens
1.4.3.22 Semicarbazide 0.1 mM, 99% inhibition, oxidation of histamine Homo sapiens
1.4.3.22 tranylcypromine slight Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.22 90000
-
 2 * 90000, SDS-PAGE Homo sapiens
1.4.3.22 200000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.22 affinity chromatography on cadaverine-Sepharose Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.22 blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 1,4-diaminobutane + H2O + O2
-
 Homo sapiens 4-aminobutanal + NH3 + H2O2
-
 ?
1.4.3.22 histamine + H2O + O2
-
 Homo sapiens (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 RCH2NH2 + H2O + O2 no activity with benzylamine Homo sapiens RCHO + NH3 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.22 dimer 2 * 90000, SDS-PAGE Homo sapiens