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Literature summary extracted from
- Purification and characterization of aminopeptidase M from muscle and mucosa of the pig intestine (1995), J. Gastroenterol., 30, 696-704.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.2 | 1,10-phenanthroline | - |
Sus scrofa |  |
| 3.4.11.2 | actinonin | almost complete inhibition at 0.1 mM | Sus scrofa | |
| 3.4.11.2 | amastatin | almost complete inhibition at 0.001 mM | Sus scrofa | |
| 3.4.11.2 | bestatin | almost complete inhibition at 0.1 mM | Sus scrofa | |
| 3.4.11.2 | EDTA | 27-30% inhibition at 1 mM | Sus scrofa | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.11.2 | membrane | mucosal membrane | Sus scrofa | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.2 | aminoacyl peptide | Sus scrofa | - |
? | - |
? | |
| 3.4.11.2 | enkephalin | Sus scrofa | may be involved in enkephalin neurotransmitter inactivation | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.2 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.2 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.11.2 | intestine | - |
Sus scrofa | - |
| 3.4.11.2 | muscle | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.2 | 3 | 3.9 | Leu5-enkephalin as substrate | Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.2 | aminoacyl peptide | - |
Sus scrofa | ? | - |
? | |
| 3.4.11.2 | enkephalin | may be involved in enkephalin neurotransmitter inactivation | Sus scrofa | ? | - |
? | |
| 3.4.11.2 | Leu5-enkephalin + H2O | - |
Sus scrofa | tyrosin + (2-5)Leu5-enkephalin | - |
? | |
| 3.4.11.2 | Met5-enkephalin + H2O | - |
Sus scrofa | tyrosin + (2-5)Met5-enkephalin | - |
? | |
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