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Literature summary extracted from

  • Nanjo, H.; Adachi, H.; Morihana, S.; Mizoguchi, T.; Nishihara, T.; Terada, T.
    Enzymic characterization of a novel bovine liver dihydrodiol dehydrogenase - reaction mechanism and bile acid dehydrogenase activity (1995), Biochim. Biophys. Acta, 1244, 53-61.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.20 additional information DD3, product inhibition studies Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.20 0.0016
-
 lithocholic acid DD1 Bos taurus
1.3.1.20 0.0038
-
 taurolithocholic acid DD1 Bos taurus
1.3.1.20 0.0045
-
 chenodeoxycholic acid DD1 Bos taurus
1.3.1.20 0.0045
-
 deoxycholic acid DD1 Bos taurus
1.3.1.20 0.017
-
 lithocholic acid DD3 Bos taurus
1.3.1.20 0.018
-
 taurochenodeoxycholic acid DD1 Bos taurus
1.3.1.20 0.033
-
 taurolithocholic acid DD3 Bos taurus
1.3.1.20 0.16
-
 cholic acid DD1 Bos taurus
1.3.1.20 0.21
-
 taurocholic acid DD1 Bos taurus
1.3.1.20 0.28
-
 trans-benzenedihydrodiol
-
 Bos taurus
1.3.1.20 0.33
-
 (S)-1-indanol DD3 Bos taurus
1.3.1.20 0.54
-
 1-Acenaphthenol DD3 Bos taurus
1.3.1.20 0.89
-
 taurochenodeoxycholic acid DD3 Bos taurus
1.3.1.20 1.5
-
 trans-naphthalenedihydrodiol DD3 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.20 cytoplasm
-
 Bos taurus 5737
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.20 Bos taurus
-
 DD1 and DD3
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.20 DD1 and DD3 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.20 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.20 (S)-indan-1-ol + NADP+ DD3 Bos taurus ?
-
 ?
1.3.1.20 1-acenaphthenol + NAD(P)+ DD3 Bos taurus ?
-
 ?
1.3.1.20 chenodeoxycholic acid + NADP+ DD1 Bos taurus ?
-
 ?
1.3.1.20 cholic acid + NADP+ DD1 Bos taurus ?
-
 ?
1.3.1.20 deoxycholic acid + NADP+ DD1 Bos taurus ?
-
 ?
1.3.1.20 lithocholic acid + NADP+ DD1, DD3 Bos taurus ?
-
 ?
1.3.1.20 taurochenodeoxycholic acid + NADP+ DD1, DD3 Bos taurus ?
-
 ?
1.3.1.20 taurocholic acid + NADP+ DD1 Bos taurus ?
-
 ?
1.3.1.20 taurolithocholic acid + NADP+ DD1, DD3 Bos taurus ?
-
 ?
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ DD3 Bos taurus catechol + NAD(P)H
-
 ?
1.3.1.20 trans-naphthalene dihydrodiol + NAD(P)+ DD3 Bos taurus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.20 DD
-
 Bos taurus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3.1.20 0.0065
-
 lithocholic acid DD1 Bos taurus
1.3.1.20 0.0115
-
 chenodeoxycholic acid DD1 Bos taurus
1.3.1.20 0.045
-
 cholic acid DD1 Bos taurus
1.3.1.20 0.07
-
 taurocholic acid DD1 Bos taurus
1.3.1.20 0.0817
-
 taurolithocholic acid DD1 Bos taurus
1.3.1.20 0.0867
-
 lithocholic acid DD3 Bos taurus
1.3.1.20 0.133
-
 deoxycholic acid DD1 Bos taurus
1.3.1.20 0.217
-
 taurolithocholic acid DD3 Bos taurus
1.3.1.20 0.367
-
 taurochenodeoxycholic acid DD1 Bos taurus
1.3.1.20 0.417
-
 (S)-1-indanol DD3 Bos taurus
1.3.1.20 0.583
-
 trans-benzene dihydrodiol DD3 Bos taurus
1.3.1.20 0.65
-
 trans-naphthalene dihydrodiol DD3 Bos taurus
1.3.1.20 0.783
-
 taurochenodeoxycholic acid DD3 Bos taurus
1.3.1.20 2
-
 1-Acenaphthenol DD3 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.20 NADP+
-
 Bos taurus
1.3.1.20 NADPH
-
 Bos taurus