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Literature summary extracted from

  • Goldstein, B.M.; Colby, T.D.
    IMP dehydrogenase: Structural aspects of inhibitor binding (1999), Curr. Med. Chem., 6, 519-536.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 benzamide riboside NAD+ binding site inhibitor Homo sapiens
1.1.1.205 additional information
-
Homo sapiens
1.1.1.205 additional information
-
Tritrichomonas suis
1.1.1.205 mycophenolate mofetil NAD+ binding site inhibitor Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.205 44000
-
-
Borreliella burgdorferi
1.1.1.205 53000
-
-
Streptococcus pyogenes
1.1.1.205 55000
-
-
Tritrichomonas suis
1.1.1.205 56000
-
-
Cricetulus griseus
1.1.1.205 56000
-
-
Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O Cricetulus griseus
-
xanthosine 5'-phosphate + NADH
-
?
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O Borreliella burgdorferi
-
xanthosine 5'-phosphate + NADH
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Borreliella burgdorferi
-
-
-
1.1.1.205 Cricetulus griseus
-
-
-
1.1.1.205 Homo sapiens
-
-
-
1.1.1.205 Streptococcus pyogenes
-
-
-
1.1.1.205 Tritrichomonas suis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
Cricetulus griseus xanthosine 5'-phosphate + NADH
-
?
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
Borreliella burgdorferi xanthosine 5'-phosphate + NADH
-
?