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Literature summary extracted from
- meta-Hydroxybenzyl-alcohol dehydrogenase (1975), Methods Enzymol., 43, 540-548.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.97 | diethyldicarbonate | 81% inhibition, NADP+ protects partly from inhibition | Penicillium urticae |  |
| 1.1.1.97 | iodoacetic acid | 54% inhibition, NADPH and NADP+ protect from inhibition | Penicillium urticae | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.97 | 0.05 | - |
3-Hydroxybenzyl alcohol | - |
Penicillium urticae | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.97 | 3-hydroxybenzyl alcohol + NADP+ | Penicillium urticae | - |
3-hydroxybenzaldehyde + NADPH | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.97 | Penicillium urticae | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.97 | streptomycin sulfate, ammonium sulfate, Sephadex G-200, 6.55fold purification | Penicillium urticae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.97 | 3-hydroxybenzyl alcohol + NADP+ | - |
Penicillium urticae | 3-hydroxybenzaldehyde + NADPH | - |
r | |
| 1.1.1.97 | 3-hydroxybenzyl alcohol + NADP+ | reduction of 3-hydroxybenzaldehyde is clearly favoured | Penicillium urticae | 3-hydroxybenzaldehyde + NADPH | - |
r | |
| 1.1.1.97 | 3-methoxybenzyl alcohol + NADP+ | - |
Penicillium urticae | 3-methoxybenzaldehyde + NADPH | - |
r | |
| 1.1.1.97 | 4-hydroxybenzyl alcohol + NADP+ | 10% activity compared to 3-hydroxybenzyl alcohol | Penicillium urticae | 4-hydroxybenzaldehyde + NADPH | - |
r | |
| 1.1.1.97 | benzyl alcohol + NADP+ | 20% activity compared to 3-hydroxybenzyl alcohol | Penicillium urticae | benzaldehyde + NADPH | - |
r | |
| 1.1.1.97 | ethanol + NADP+ | 29% activity compared to 3-hydroxybenzyl alcohol | Penicillium urticae | acetaldehyde + NADPH + H+ | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.97 | 7.6 | - |
- |
Penicillium urticae |
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Release 2023.1 (January 2023)
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