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Literature summary extracted from

  • Hollander, V.P.
    Acid phosphatases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 4, 449-498.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.2 citrate
-
 Escherichia coli
3.1.3.2 citrate slight activation Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.1.3.2
-
 Rattus norvegicus

General Stability

EC Number General Stability Organism
3.1.3.2 loses more than 90% of activity in 3 M urea at 25°C, pH 7.0 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.2 2-hydroyxy-5-nitrobenzyl bromide
-
 Homo sapiens
3.1.3.2 arsenate
-
 Bos taurus
3.1.3.2 arsenate
-
 Homo sapiens
3.1.3.2 arsenate
-
 Saccharomyces mellis
3.1.3.2 Borate
-
 Saccharomyces mellis
3.1.3.2 Bromosuccinimide
-
 Homo sapiens
3.1.3.2 Cu2+
-
 Bos taurus
3.1.3.2 Cu2+
-
 Homo sapiens
3.1.3.2 Cu2+
-
 Rattus norvegicus
3.1.3.2 cyanide
-
 Homo sapiens
3.1.3.2 diisopropyl flurophosphate
-
 Homo sapiens
3.1.3.2 F- competitive Bos taurus
3.1.3.2 F-
-
 Drosophila melanogaster
3.1.3.2 F-
-
 Escherichia coli
3.1.3.2 F-
-
 Homo sapiens
3.1.3.2 F-
-
 Lupinus luteus
3.1.3.2 F- competitive Neurospora crassa
3.1.3.2 F-
-
 Nicotiana tabacum
3.1.3.2 F-
-
 Rattus norvegicus
3.1.3.2 F-
-
 Staphylococcus aureus
3.1.3.2 Fe2+
-
 Bos taurus
3.1.3.2 Fe2+
-
 Homo sapiens
3.1.3.2 Fe2+
-
 Rattus norvegicus
3.1.3.2 ICl
-
 Homo sapiens
3.1.3.2 Mg2+
-
 Bos taurus
3.1.3.2 Mg2+
-
 Homo sapiens
3.1.3.2 molybdate
-
 Bos taurus
3.1.3.2 molybdate
-
 Homo sapiens
3.1.3.2 molybdate
-
 Lupinus luteus
3.1.3.2 molybdate
-
 Neurospora crassa
3.1.3.2 molybdate
-
 Nicotiana tabacum
3.1.3.2 molybdate
-
 Rattus norvegicus
3.1.3.2 molybdate
-
 Saccharomyces mellis
3.1.3.2 molybdate
-
 Staphylococcus aureus
3.1.3.2 oxalate
-
 Homo sapiens
3.1.3.2 oxalate
-
 Neurospora crassa
3.1.3.2 oxalate
-
 Rattus norvegicus
3.1.3.2 p-mercuribenzoate
-
 Homo sapiens
3.1.3.2 phosphate
-
 Bos taurus
3.1.3.2 phosphate
-
 Drosophila melanogaster
3.1.3.2 phosphate
-
 Homo sapiens
3.1.3.2 phosphate
-
 Lupinus luteus
3.1.3.2 phosphate
-
 Nicotiana tabacum
3.1.3.2 phosphate
-
 Rattus norvegicus
3.1.3.2 phosphate
-
 Saccharomyces mellis
3.1.3.2 phosphate
-
 Staphylococcus aureus
3.1.3.2 Tartrate
-
 Bos taurus
3.1.3.2 Tartrate
-
 Drosophila melanogaster
3.1.3.2 Tartrate
-
 Escherichia coli
3.1.3.2 Tartrate inhibition of enzyme from prostate, no inhibition of enzyme from erythrocytes Homo sapiens
3.1.3.2 Tartrate D-(+)-tartrate Neurospora crassa
3.1.3.2 Tartrate D-(+)-tartrate Rattus norvegicus
3.1.3.2 taurocholate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.2 0.75
-
 p-nitrophenyl phosphate
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.2 lysosome
-
 Homo sapiens 5764
-
3.1.3.2 lysosome
-
 Rattus norvegicus 5764
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.2 16590
-
 equilibrium sedimentation Bos taurus
3.1.3.2 58000
-
 gel filtration Staphylococcus aureus
3.1.3.2 89100
-
 sucrose density gradient centrifugation Homo sapiens
3.1.3.2 100000
-
-
 Homo sapiens
3.1.3.2 100000
-
 sucrose density gradient centrifugation, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.2 Bos taurus
-
-
-
3.1.3.2 Chaos carolinense
-
-
-
3.1.3.2 Drosophila melanogaster
-
-
-
3.1.3.2 Escherichia coli
-
-
-
3.1.3.2 Homo sapiens
-
-
-
3.1.3.2 Lupinus luteus
-
-
-
3.1.3.2 Mus musculus
-
-
-
3.1.3.2 Neurospora crassa
-
-
-
3.1.3.2 Nicotiana tabacum
-
-
-
3.1.3.2 Rattus norvegicus
-
-
-
3.1.3.2 Saccharomyces cerevisiae
-
-
-
3.1.3.2 Saccharomyces mellis
-
-
-
3.1.3.2 Staphylococcus aureus
-
 PS 55
-
3.1.3.2 Staphylococcus aureus PS 55
-
 PS 55
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.2
-
 Staphylococcus aureus
3.1.3.2
-
 Rattus norvegicus
3.1.3.2
-
 Neurospora crassa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.2 erythrocyte
-
 Homo sapiens
-
3.1.3.2 leaf
-
 Nicotiana tabacum
-
3.1.3.2 liver
-
 Staphylococcus aureus
-
3.1.3.2 liver
-
 Homo sapiens
-
3.1.3.2 liver
-
 Rattus norvegicus
-
3.1.3.2 liver
-
 Bos taurus
-
3.1.3.2 liver Kupffer cells Mus musculus
-
3.1.3.2 prostate gland
-
 Homo sapiens
-
3.1.3.2 prostate gland
-
 Rattus norvegicus
-
3.1.3.2 seedling
-
 Lupinus luteus
-
3.1.3.2 semen
-
 Homo sapiens
-
3.1.3.2 serum
-
 Rattus norvegicus
-
3.1.3.2 serum
-
 Bos taurus
-
3.1.3.2 spleen
-
 Homo sapiens
-
3.1.3.2 spleen
-
 Rattus norvegicus
-
3.1.3.2 spleen
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.2 additional information
-
-
 Homo sapiens
3.1.3.2 additional information
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
3.1.3.2 -25°C, pH 6.0, stable for years Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.2 2',3'-AMP + H2O
-
 Bos taurus ?
-
 ?
3.1.3.2 2-glycerophosphate + H2O
-
 Homo sapiens glycerol + phosphate
-
 ?
3.1.3.2 2-glycerophosphate + H2O
-
 Rattus norvegicus glycerol + phosphate
-
 ?
3.1.3.2 2-glycerophosphate + H2O
-
 Bos taurus glycerol + phosphate
-
 ?
3.1.3.2 2-glycerophosphate + H2O
-
 Neurospora crassa glycerol + phosphate
-
 ?
3.1.3.2 5'-AMP + H2O
-
 Bos taurus adenosine + phosphate
-
 ?
3.1.3.2 5'-UMP + H2O 5% of the activity with p-nitrophenyl phosphate Bos taurus uridine + phosphate
-
 ?
3.1.3.2 alpha-glycerophosphate + H2O
-
 Staphylococcus aureus glycerol + phosphate
-
 ?
3.1.3.2 alpha-glycerophosphate + H2O
-
 Rattus norvegicus glycerol + phosphate
-
 ?
3.1.3.2 alpha-glycerophosphate + H2O
-
 Bos taurus glycerol + phosphate
-
 ?
3.1.3.2 alpha-glycerophosphate + H2O
-
 Neurospora crassa glycerol + phosphate
-
 ?
3.1.3.2 alpha-glycerophosphate + H2O
-
 Staphylococcus aureus PS 55 glycerol + phosphate
-
 ?
3.1.3.2 FMN + H2O
-
 Rattus norvegicus ?
-
 ?
3.1.3.2 FMN + H2O 68% of the activity with p-nitrophenyl phosphate Bos taurus ?
-
 ?
3.1.3.2 galactose 6-phosphate + H2O 39% of the activity with p-nitrophenyl phosphate Bos taurus galactose + phosphate
-
 ?
3.1.3.2 glucose 1-phosphate + H2O
-
 Escherichia coli glucose + phosphate
-
 ?
3.1.3.2 glucose 1-phosphate + H2O
-
 Homo sapiens glucose + phosphate
-
 ?
3.1.3.2 glucose 1-phosphate + H2O
-
 Bos taurus glucose + phosphate
-
 ?
3.1.3.2 glucose 1-phosphate + H2O
-
 Lupinus luteus glucose + phosphate
-
 ?
3.1.3.2 glucose 1-phosphate + H2O
-
 Nicotiana tabacum glucose + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Staphylococcus aureus p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Escherichia coli p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Homo sapiens p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Rattus norvegicus p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Bos taurus p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Lupinus luteus p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Nicotiana tabacum p-nitrophenol + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Staphylococcus aureus PS 55 p-nitrophenol + phosphate
-
 ?
3.1.3.2 phenyl phosphate + H2O
-
 Homo sapiens phenol + phosphate
-
 ?
3.1.3.2 phenyl phosphate + H2O
-
 Rattus norvegicus phenol + phosphate
-
 ?
3.1.3.2 phenyl phosphate + H2O
-
 Bos taurus phenol + phosphate
-
 ?
3.1.3.2 phenyl phosphate + H2O
-
 Lupinus luteus phenol + phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.2 5.5
-
-
 Homo sapiens
3.1.3.2 5.5
-
-
 Bos taurus
3.1.3.2 5.6
-
 hydrolysis of 2-glycerophosphate Neurospora crassa