Any feedback?
Literature summary for 7.4.2.8 extracted from
- Identification of small-molecule inhibitors of Yersinia pestis type III secretion system YscN ATPase (2011), PLoS ONE, 6, e19716.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Yersinia pestis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | identification of small molecule inhibitors with IC50 values below 0.02 mM in an in vitro ATPase assay | Yersinia pestis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Yersinia pestis | - |
type III secretion system YscN ATPase | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| YscN | - |
Yersinia pestis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | deletion of the catalytic domain of the yscN gene in Yersinia pestis CO92 attenuated the strain over three million-fold in the Swiss-Webster mouse model of bubonic plague | Yersinia pestis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
