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Literature summary for 7.4.2.8 extracted from

  • Wagner, S.; Stenta, M.; Metzger, L.C.; Dal Peraro, M.; Cornelis, G.R.
    Length control of the injectisome needle requires only one molecule of Yop secretion protein P (YscP) (2010), Proc. Natl. Acad. Sci. USA, 107, 13860-13865.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Yersinia enterocolitica LJ4036, a strain in which the wild-type copy of yscP is deleted from the virulence plasmid Yersinia sp.

Protein Variants

Protein Variants Comment Organism
additional information three different strains expressing simultaneously a short and a long version of YscP are engineered (Short YscP protein,YscP388: the spacer between the two export signals and one copy of the repeats in the central part are removed. Long YscP, yscP686: a restriction cleavage site between codons 250 and 251 in the central part of the yscP gene is engineered. A copy of codons 214-374, encoding the repeated region, into the restriction site is inserted). Genetic evidence is provided that only one molecule of YscP is required to control the length of one injectisome needle, thus supporting the static model of needle length regulation Yersinia sp.

Organism

Organism UniProt Comment Textmining
Yersinia sp.
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-
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
Yop secretion protein
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Yersinia sp.
YscP
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Yersinia sp.