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Literature summary for 7.4.2.5 extracted from

  • Izaguirre, G.; Hansen, J.N.
    Use of alkaline phosphatase as a reporter polypeptide to study the role of the subtilin leader segment and the SpaT transporter in the posttranslational modifications and secretion of subtilin in Bacillus subtilis 168 (1997), Appl. Environ. Microbiol., 63, 3965-3971.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.5

Cloned(Commentary)

Cloned (Comment) Organism
subtilin gene Bacillus subtilis

Protein Variants

Protein Variants Comment Organism
additional information large in-frame deletion of SpaT, not translocation is interrupted, but proteolytic cleavage of the leader segment while the precurser resides in the cell wall Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + subtilisin/in Bacillus subtilis
-
 ADP + phosphate + subtilisin/out
-
 ?
ATP + H2O + subtilisin/in Bacillus subtilis 168
-
 ADP + phosphate + subtilisin/out
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Bacillus subtilis 168
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + subtilisin/in
-
 Bacillus subtilis ADP + phosphate + subtilisin/out
-
 ?
ATP + H2O + subtilisin/in
-
 Bacillus subtilis 168 ADP + phosphate + subtilisin/out
-
 ?

Subunits

Subunits Comment Organism
More ABC transporter Bacillus subtilis
More SpaT, another ABC transporter encoded in the subtilin operon, role concluded from homologies to other ABC transporters Bacillus subtilis