Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Trypanosoma brucei |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-naphthoic acid | - |
Trypanosoma brucei | |
2-nitronaphthalene | - |
Trypanosoma brucei | |
4,5-dihydroxynaphthalene-2,7-disulfonate | - |
Trypanosoma brucei | |
4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]-7-[(1-phenylethenyl)amino]naphthalene-2-sulfonic acid | - |
Trypanosoma brucei | |
6-hydroxy-5-[(E)-[3-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]-5-sulfophenyl]diazenyl]naphthalene-2-sulfonic acid | - |
Trypanosoma brucei | |
7,7'-iminobis(4-hydroxynaphthalene-2-sulfonic acid) | - |
Trypanosoma brucei | |
7-amino-4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]naphthalene-2-sulfonic acid | - |
Trypanosoma brucei | |
naphthalene-2-sulfonic acid | - |
Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | P86927 | - |
- |
Purification (Comment) | Organism |
---|---|
purified via a C-terminal tandem affinity purification tag | Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (ribonucleotide)n + (ribonucleotide)m | - |
Trypanosoma brucei | AMP + diphosphate + (ribonucleotide)n+m | - |
? |
Synonyms | Comment | Organism |
---|---|---|
REL1 | - |
Trypanosoma brucei |
RNA editing ligase 1 | - |
Trypanosoma brucei |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00153 | - |
pH and temperature not specified in the publication | Trypanosoma brucei | 7-amino-4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]naphthalene-2-sulfonic acid | |
0.00159 | - |
pH and temperature not specified in the publication | Trypanosoma brucei | 6-hydroxy-5-[(E)-[3-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]-5-sulfophenyl]diazenyl]naphthalene-2-sulfonic acid | |
0.00216 | - |
pH and temperature not specified in the publication | Trypanosoma brucei | 4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]-7-[(1-phenylethenyl)amino]naphthalene-2-sulfonic acid | |
0.00836 | - |
pH and temperature not specified in the publication | Trypanosoma brucei | 7,7'-iminobis(4-hydroxynaphthalene-2-sulfonic acid) |
General Information | Comment | Organism |
---|---|---|
physiological function | RNA editing ligase 1 is a key component of the trypanosomatid editosome | Trypanosoma brucei |