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Literature summary for 6.5.1.3 extracted from

  • Gao, G.; Simpson, A.M.; Kang, X.; Rogers, K.; Nebohacova, M.; Li, F.; Simpson, L.
    Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase (2005), Proc. Natl. Acad. Sci. USA, 102, 4712-4717.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
enzymatically active Leishmania tarentolae REL1 and REL2 and Trypanosoma brucei REL1 proteins from a Baculovirus expression system. The recombinant proteins can each integrate into an L-complex that has been depleted of the cognate ligase by RNAi. In the case of REL1, the integration of the recombinant enzyme functionally complements the REL1-depleted L-complex in an in vitro editing system Trypanosoma brucei
enzymatically active Leishmania tarentolae REL1 and REL2 and Trypanosoma brucei REL1 proteins from a Baculovirus expression system. The recombinant proteins can each integrate into an L-complex that has been depleted of the cognate ligase by RNAi. In the case of REL1, the integration of the recombinant enzyme functionally complements the REL1-depleted L-complex in an in vitro editing system Leishmania tarentolae

Organism

Organism UniProt Comment Textmining
Leishmania tarentolae
-
-
-
Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (ribonucleotide)n + (ribonucleotide)m
-
Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m
-
?
ATP + (ribonucleotide)n + (ribonucleotide)m
-
Leishmania tarentolae AMP + diphosphate + (ribonucleotide)n+m
-
?