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Literature summary for 6.5.1.1 extracted from

  • Tan, G.T.; Lee, S.; Lee, I.S.; Chen, J.; Leitner, P.; Besterman, J.; Kinghorn, A.D.; Pezzuto, J.M.
    Natural-product inhibitors of human DNA ligase I (1996), Biochem. J., 314, 993-1000.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
aleuritolic acid
-
Homo sapiens
chelerythrine chloride
-
Homo sapiens
Fagaronine chloride
-
Homo sapiens
Fulvoplumierin
-
Homo sapiens
morin
-
Homo sapiens
myricetin
-
Homo sapiens
Nitidine chloride
-
Homo sapiens
oleanolic acid
-
Homo sapiens
Protolichesterinic acid
-
Homo sapiens
Sanguinarine nitrate
-
Homo sapiens
Swertifrancheside
-
Homo sapiens
ursolic acid
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
DNA ligase I
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
Homo sapiens AMP + diphosphate + (deoxyribonucleotide)n+m
-
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