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Literature summary for 6.5.1.1 extracted from

  • Johnson, A.P.; Fairman, M.P.
    The identification and purification of a novel mammalian DNA ligase (1997), Mutat. Res., 383, 205-212.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
x * 44000, DNA ligase V, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DNA ligase V Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m DNA ligase V does not join nicked templates with high efficiency, but can join double-strand breaks with a similar efficiency to DNA ligase I Homo sapiens AMP + diphosphate + (deoxyribonucleotide)n+m
-
?

Subunits

Subunits Comment Organism
? x * 44000, DNA ligase V, SDS-PAGE Homo sapiens