Literature summary for 6.4.1.6 extracted from

Brahmachary, P.; Wang, G.; Benoit, S.L.; Weinberg, M.V.; Maier, R.J.; Hoover, T.R.
The human gastric pathogen Helicobacter pylori has a potential acetone carboxylase that enhances its ability to colonize mice (2008), BMC Microbiol., 8, 14.

Search for more literature for 6.4.1.6

Application

Application	Comment	Organism
medicine	inactivation of operon acxABC encoding acetone carboxylase with a chloramphenicol resistance cassette. In mouse colonization studies the numbers of Helicobacter pylori recovered from mice inoculated with the acxB:cat mutant are generally one to two orders of magnitude lower than those recovered from mice inoculated with the parental strain	Helicobacter pylori

Protein Variants

Protein Variants	Comment	Organism
additional information	inactivation of operon acxABC encoding acetone carboxylase with a chloramphenicol resistance cassette. In mouse colonization studies the numbers of Helicobacter pylori recovered from mice inoculated with the acxB:cat mutant are generally one to two orders of magnitude lower than those recovered from mice inoculated with the parental strain	Helicobacter pylori

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Helicobacter pylori	operon acxABC encoding acetone carboxylase is involved in survival of the bacterium in stomach	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Helicobacter pylori	-	mouse-adapted strain SSI	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	operon acxABC encoding acetone carboxylase is involved in survival of the bacterium in stomach	Helicobacter pylori	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)