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Literature summary for 6.4.1.3 extracted from

  • Menendez, C.; Bauer, Z.; Huber, H.; Gad'on, N.; Stetter, K.O.; Fuchs, G.
    Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation (1999), J. Bacteriol., 181, 1088-1098.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Chloroflexus aurantiacus
Mg2+ required Metallosphaera sedula
Mg2+ required Sulfuracidifex metallicus
Mg2+ required Acidianus infernus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + propanoyl-CoA + HCO3- Chloroflexus aurantiacus CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Metallosphaera sedula CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Sulfuracidifex metallicus CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Acidianus infernus CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Acidianus infernus So4a / DSM 3191 CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Sulfuracidifex metallicus Kra23 / DSM 6482 CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Metallosphaera sedula TH2 / ATCC 51363 / DSM 5348 CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- Chloroflexus aurantiacus OK-70-fl / DSM 636 CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle ADP + phosphate + (S)-methylmalonyl-CoA
-
?

Organism

Organism UniProt Comment Textmining
Acidianus infernus
-
-
-
Acidianus infernus So4a / DSM 3191
-
-
-
Chloroflexus aurantiacus
-
-
-
Chloroflexus aurantiacus OK-70-fl / DSM 636
-
-
-
Metallosphaera sedula
-
-
-
Metallosphaera sedula TH2 / ATCC 51363 / DSM 5348
-
-
-
Sulfuracidifex metallicus
-
-
-
Sulfuracidifex metallicus Kra23 / DSM 6482
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + propanoyl-CoA + HCO3-
-
Chloroflexus aurantiacus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Metallosphaera sedula ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Sulfuracidifex metallicus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Acidianus infernus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Chloroflexus aurantiacus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Metallosphaera sedula ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Sulfuracidifex metallicus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Acidianus infernus ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Acidianus infernus So4a / DSM 3191 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Acidianus infernus So4a / DSM 3191 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Sulfuracidifex metallicus Kra23 / DSM 6482 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Sulfuracidifex metallicus Kra23 / DSM 6482 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Metallosphaera sedula TH2 / ATCC 51363 / DSM 5348 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Metallosphaera sedula TH2 / ATCC 51363 / DSM 5348 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3-
-
Chloroflexus aurantiacus OK-70-fl / DSM 636 ADP + phosphate + (S)-methylmalonyl-CoA
-
?
ATP + propanoyl-CoA + HCO3- CO2 fixation during autotrophic growth, enzyme of the 3-hydroxypropionate cycle Chloroflexus aurantiacus OK-70-fl / DSM 636 ADP + phosphate + (S)-methylmalonyl-CoA
-
?

Cofactor

Cofactor Comment Organism Structure
biotin bound to enzyme Chloroflexus aurantiacus
biotin bound to enzyme Metallosphaera sedula
biotin bound to enzyme Sulfuracidifex metallicus
biotin bound to enzyme Acidianus infernus