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Literature summary for 6.4.1.2 extracted from
- Molecular cloning and characterization of two genes for the biotin carboxylase and carboxyltransferase subunits of acetyl coenzyme A carboxylase in Myxococcus xanthus (2000), J. Bacteriol., 182, 5462-5469.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| carboxyltransferase and biotin carboxylase subunit, expressed in Escherichia coli | Myxococcus xanthus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 58100 | - |
carboxyltransferase subunit, calculated from amino acid sequence | Myxococcus xanthus |
| 61500 | - |
biotin carboxylase subunit, calculated from amino acid sequence | Myxococcus xanthus |
| 65000 | - |
biotin carboxylase subunit, SDS-PAGE | Myxococcus xanthus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetyl-CoA + HCO3- | Myxococcus xanthus | key enzyme of fatty acid biosynthesis | ADP + phosphate + malonyl-CoA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Myxococcus xanthus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetyl-CoA + HCO3- | - |
Myxococcus xanthus | ADP + phosphate + malonyl-CoA | - |
? | |
| ATP + acetyl-CoA + HCO3- | key enzyme of fatty acid biosynthesis | Myxococcus xanthus | ADP + phosphate + malonyl-CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| multimer | - |
Myxococcus xanthus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| biotin | enzyme-bound | Myxococcus xanthus | |
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