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Literature summary for 6.4.1.2 extracted from

  • Hellyer, A.; Bambridge, H.E.; Slabas, A.R.
    Plant acetyl-CoA carboxylase (1986), Biochem. Soc. Trans., 14, 565-568.
    View publication on PubMed
Search for more literature for 6.4.1.2

General Stability

General Stability Organism
20% glycerol as well as PMSF prevent rapid loss of activity Brassica napus

Inhibitors

Inhibitors Comment Organism Structure
ADP
-
 Triticum aestivum
ADP
-
 Zea mays
AMP
-
 Triticum aestivum
AMP
-
 Zea mays

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21000
-
 x * 21000 + x * 31000 + x * 41000, phenol/acetic acid/urea gel Hordeum vulgare
31000
-
 x * 21000 + x * 31000 + x * 41000, phenol/acetic acid/urea gel Hordeum vulgare
41000
-
 x * 21000 + x * 31000 + x * 41000, phenol/acetic acid/urea gel Hordeum vulgare
220000
-
 x * 220000, SDS-PAGE Brassica napus
240000
-
 x * 240000, SDS-PAGE Triticum aestivum
500000
-
 gel filtration Zea mays
610000
-
-
 Hordeum vulgare

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + acetyl-CoA + HCO3- Triticum aestivum
-
 ?
-
 ?
ATP + acetyl-CoA + HCO3- Hordeum vulgare
-
 ?
-
 ?
ATP + acetyl-CoA + HCO3- Zea mays
-
 ?
-
 ?
ATP + acetyl-CoA + HCO3- Petroselinum crispum
-
 ?
-
 ?
ATP + acetyl-CoA + HCO3- Brassica napus first committed step in biosynthesis of fatty acids, providing the essential substrate for fatty acid synthetase ?
-
 ?

Organism

Organism UniProt Comment Textmining
Brassica napus
-
-
-
Hordeum vulgare
-
-
-
Persea americana
-
-
-
Petroselinum crispum
-
-
-
Ricinus communis
-
-
-
Triticum aestivum
-
-
-
Zea mays
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Hordeum vulgare
-
leaf
-
 Zea mays
-
seed
-
 Triticum aestivum
-
seed
-
 Brassica napus
-
seed
-
 Ricinus communis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetyl-CoA + HCO3-
-
 Triticum aestivum ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Hordeum vulgare ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Zea mays ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Petroselinum crispum ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Brassica napus ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Ricinus communis ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Persea americana ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Triticum aestivum ?
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Hordeum vulgare ?
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Zea mays ?
-
 ?
ATP + acetyl-CoA + HCO3-
-
 Petroselinum crispum ?
-
 ?
ATP + acetyl-CoA + HCO3- first committed step in biosynthesis of fatty acids, providing the essential substrate for fatty acid synthetase Brassica napus ?
-
 ?

Subunits

Subunits Comment Organism
?
-
 Zea mays
?
-
 Petroselinum crispum
?
-
 Persea americana
? x * 220000, SDS-PAGE Brassica napus
? x * 240000, SDS-PAGE Triticum aestivum
? x * 21000 + x * 31000 + x * 41000, phenol/acetic acid/urea gel Hordeum vulgare

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Brassica napus

Cofactor

Cofactor Comment Organism Structure
biotin biotin-containing enzyme Triticum aestivum
biotin biotin-containing enzyme Hordeum vulgare
biotin biotin-containing enzyme Zea mays
biotin biotin-containing enzyme Petroselinum crispum
biotin biotin-containing enzyme Brassica napus
biotin biotin-containing enzyme Ricinus communis
biotin biotin-containing enzyme Persea americana