Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Asp-tRNAAsn + ? | Methanothermobacter thermautotrophicus | - |
Asn-tRNAAsn + ? | - |
? | |
Asp-tRNAAsn + ? | Thermus thermophilus | AdT is related to the biosynthesis of asparagine rather than to provide charged tRNA for protein biosynthesis | Asn-tRNAAsn + ? | - |
? | |
Asp-tRNAAsn + ? | Deinococcus radiodurans | AdT is related to the biosynthesis of asparagine rather than to provide charged tRNA for protein biosynthesis | Asn-tRNAAsn + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aeropyrum pernix | - |
- |
- |
Archaeoglobus fulgidus | - |
- |
- |
Bacillus subtilis | - |
- |
- |
Deinococcus radiodurans | - |
- |
- |
Methanocaldococcus jannaschii | - |
- |
- |
Methanothermobacter thermautotrophicus | - |
Methanobacterium thermoautotrophicum | - |
Thermus thermophilus | - |
recombinant enzyme | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Asp-tRNAAsn + ? | - |
Methanothermobacter thermautotrophicus | Asn-tRNAAsn + ? | - |
? | |
Asp-tRNAAsn + ? | AdT is related to the biosynthesis of asparagine rather than to provide charged tRNA for protein biosynthesis | Thermus thermophilus | Asn-tRNAAsn + ? | - |
? | |
Asp-tRNAAsn + ? | AdT is related to the biosynthesis of asparagine rather than to provide charged tRNA for protein biosynthesis | Deinococcus radiodurans | Asn-tRNAAsn + ? | - |
? | |
ATP + Asp-tRNAAsn + glutamine | - |
Bacillus subtilis | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | - |
Methanothermobacter thermautotrophicus | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | - |
Methanocaldococcus jannaschii | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | - |
Archaeoglobus fulgidus | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | - |
Aeropyrum pernix | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | dual-specific Asp/Glu-AdT is able to amidate both mischarged tRNAGln and tRNAAsn, but functions as Asp-AdT | Thermus thermophilus | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Asp-tRNAAsn + glutamine | dual-specific Asp/Glu-AdT is able to amidate both mischarged tRNAGln and tRNAAsn, but functions as Asp-AdT | Deinococcus radiodurans | ADP + phosphate + Asn-tRNAAsn + glutamate | - |
? | |
ATP + Glu-tRNAGln + glutamine | - |
Bacillus subtilis | ADP + Gln-tRNAGln + glutamate + phosphate | - |
? | |
ATP + Glu-tRNAGln + glutamine | - |
Methanothermobacter thermautotrophicus | ADP + Gln-tRNAGln + glutamate + phosphate | - |
? | |
ATP + Glu-tRNAGln + glutamine | dual-specific Asp/Glu-AdT is able to amidate both mischarged tRNAGln and tRNAAsn, but functions as Asp-AdT | Thermus thermophilus | ADP + Gln-tRNAGln + glutamate + phosphate | - |
? | |
ATP + Glu-tRNAGln + glutamine | dual-specific Asp/Glu-AdT is able to amidate both mischarged tRNAGln and tRNAAsn, but functions as Asp-AdT | Deinococcus radiodurans | ADP + Gln-tRNAGln + glutamate + phosphate | - |
? | |
additional information | enzyme specificity depends on the biochemical context, i.e. on the availability of the mischarged aminoacyl-tRNA substrate, which is controlled by the presence of a nondiscriminating GluRS or AspRS | Thermus thermophilus | ? | - |
? | |
additional information | enzyme specificity depends on the biochemical context, i.e. on the availability of the mischarged aminoacyl-tRNA substrate, which is controlled by the presence of a nondiscriminating GluRS or AspRS | Deinococcus radiodurans | ? | - |
? | |
additional information | archaeal enzyme resembles the bacterial Glu/Asp-AdT, but can only amidate Asp-tRNAAsn and not Glu-tRNAGln | Methanothermobacter thermautotrophicus | ? | - |
? | |
additional information | archaeal enzyme resembles the bacterial Glu/Asp-AdT, but can only amidate Asp-tRNAAsn and not Glu-tRNAGln | Methanocaldococcus jannaschii | ? | - |
? | |
additional information | archaeal enzyme resembles the bacterial Glu/Asp-AdT, but can only amidate Asp-tRNAAsn and not Glu-tRNAGln | Archaeoglobus fulgidus | ? | - |
? | |
additional information | archaeal enzyme resembles the bacterial Glu/Asp-AdT, but can only amidate Asp-tRNAAsn and not Glu-tRNAGln | Aeropyrum pernix | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotrimer | - |
Bacillus subtilis |
heterotrimer | - |
Thermus thermophilus |
heterotrimer | - |
Deinococcus radiodurans |
heterotrimer | ORFs corresponding to a heterotrimeric amidotransferase resembling the bacterial Glu/Asp-AdT | Methanothermobacter thermautotrophicus |
heterotrimer | ORFs corresponding to a heterotrimeric amidotransferase resembling the bacterial Glu/Asp-AdT | Methanocaldococcus jannaschii |
heterotrimer | ORFs corresponding to a heterotrimeric amidotransferase resembling the bacterial Glu/Asp-AdT | Archaeoglobus fulgidus |
heterotrimer | ORFs corresponding to a heterotrimeric amidotransferase resembling the bacterial Glu/Asp-AdT | Aeropyrum pernix |