Protein Variants | Comment | Organism |
---|---|---|
additional information | supressor of black mutation, Su(b), which causes a loss of UTP feedback inhibition, is a missense mutation resulting in a glutamate to lysine substitution within the second ATP binding site of enzyme | Drosophila melanogaster |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
UTP | slight UTP inhibition of SU(b) mutant enzyme is probably due to the chelating of Mg2+ by UTP | Drosophila melanogaster |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
L-glutamine | pH 7.4, 30°C, Su(b) mutant | Drosophila melanogaster | |
0.057 | - |
L-glutamine | pH 7.4, 30°C, wild-type enzyme | Drosophila melanogaster | |
2.4 | - |
HCO3- | pH 7.4, 30°C, Su(b) mutant | Drosophila melanogaster | |
3 | - |
HCO3- | pH 7.4, 30°C, wild-type enzyme | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | P05990 | supressor of black mutation | - |
Purification (Comment) | Organism |
---|---|
partial | Drosophila melanogaster |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | - |
Drosophila melanogaster | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? |