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Literature summary for 6.3.5.2 extracted from
- Role of cyclic di-GMP in Xylella fastidiosa biofilm formation, plant virulence, and insect transmission (2010), Mol. Plant Microbe Interact., 23, 1356-63.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Xylella fastidiosa | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cgsA | - |
Xylella fastidiosa |
| di-GMP synthase A | - |
Xylella fastidiosa |
| PD0279 | - |
Xylella fastidiosa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | cgsA mutants exhibit a hyperadhesive phenotype in vitro and overexpress gumJ, hxfA, hxfB, xadA, and fimA, which promote attachment of cells to surfaces and biofilm formation. The mutants are greatly reduced in virulence to grape albeit still transmissible by insect vectors, although at a reduced level compared with transmission rates of the wild-type strain, despite the fact that similar numbers of cells of the cgsA mutant are acquired by the insects from infected plants. High levels of EPS are measured in cgsA mutants compared with wild-type strains. Scanning electron microscopy analysis reveal a thicker amorphous layer surrounding the mutants. Overexpression of cgsA in a cgsA-complement mutant conferred the opposite phenotypes in vitro | Xylella fastidiosa |
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Release 2023.1 (January 2023)
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