Literature summary for 6.3.5.2 extracted from

Tesmer, J.J.G.; Stemmler, T.L.; Penner-Hahn, J.E.; Davisson, V.J.; Smith, J.L.
Preliminary X-ray analysis of Escherichia coli GMP synthetase: determination of anomalous scattering factors for a cysteinyl mercury derivative (1994), Proteins Struct. Funct. Genet., 18, 394-403.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
azaserine	-	Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
120000	-	gel filtration	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Escherichia coli	final step of de novo guanine nucleotide biosynthesis	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + XMP + Gln	-	Escherichia coli	AMP + diphosphate + GMP + Glu	-	?
ATP + XMP + NH4+	-	Escherichia coli	AMP + diphosphate + GMP	-	?
additional information	final step of de novo guanine nucleotide biosynthesis	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)