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Literature summary for 6.3.5.10 extracted from

  • Woodson, J.D.; Zayas, C.L.; Escalante-Semerena, J.C.
    A new pathway for salvaging the coenzyme B12 precursor cobinamide in archaea requires cobinamide-phosphate synthase (CbiB) enzyme activity (2003), J. Bacteriol., 185, 7193-7201.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
cbiP gene Salmonella enterica
cbiP gene Halobacterium sp.

Protein Variants

Protein Variants Comment Organism
additional information cbiP mutants, nutritional studies Salmonella enterica
additional information mutant strain JE6738 with in-frame deletion of cbiP, deficient in cobinamide biosynthesis, auxotrophic for adenosylcorbyric acid Halobacterium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Halobacterium sp. cobinamide biosynthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Salmonella enterica involved in the de novo cobinamide biosynthesis pathway ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Halobacterium sp. NRC-1 cobinamide biosynthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Salmonella enterica TR6583 involved in the de novo cobinamide biosynthesis pathway ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Halobacterium sp.
-
strains NRC-1 and MPK414
-
Salmonella enterica
-
-
-
Salmonella enterica TR6583
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
Salmonella enterica ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
Halobacterium sp. ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobinamide biosynthesis Halobacterium sp. ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O involved in the de novo cobinamide biosynthesis pathway Salmonella enterica ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobinamide biosynthesis Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
Salmonella enterica TR6583 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O involved in the de novo cobinamide biosynthesis pathway Salmonella enterica TR6583 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
?

Synonyms

Synonyms Comment Organism
CbiP
-
Salmonella enterica
CbiP
-
Halobacterium sp.