General Stability | Organism |
---|---|
in presence of 5 mM argininosuccinate, the activities of the three forms of the enzyme are resistant to chymotrypsin | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoate) | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.022 | - |
AMP | citrulline, enzyme form ASSII | Rattus norvegicus | |
0.026 | - |
L-citrulline | enzyme form ASSI | Rattus norvegicus | |
0.037 | - |
L-Asp | enzyme form ASSII | Rattus norvegicus | |
0.038 | - |
L-Asp | enzyme form ASSI | Rattus norvegicus | |
0.11 | - |
ATP | enzyme form ASSI | Rattus norvegicus | |
0.17 | - |
ATP | enzyme form ASSII | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
48000 | - |
x * 48000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
3 enzyme forms ASSI, ASSII, and ASSIII | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-citrulline + L-Asp | - |
Rattus norvegicus | AMP + diphosphate + L-argininosuccinate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 48000, SDS-PAGE | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
enzyme forms ASSI and II are stable, enzyme form ASSIII is very unstable | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.6 | - |
reaction of ATP + citrulline + L-Asp, enzyme forms ASSI and ASSII | Rattus norvegicus |