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Literature summary for 6.3.4.12 extracted from
- Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5 (2010), Mol. Microbiol., 75, 426-439.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene gms, gsIII-like gene, DNA and amino acid sequence determination and analysis, genetic structure | Methyloversatilis universalis |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | dependent on, cannot be substituted by Mn2+ | Methyloversatilis universalis |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 48820 | - |
x * 48820, sequence calcualtion | Methyloversatilis universalis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamic acid + ethylamine | Methyloversatilis universalis | - |
theanine | i.e. gamma-glutamylethylamide | ? | |
| L-glutamic acid + ethylamine | Methyloversatilis universalis FAM5 | - |
theanine | i.e. gamma-glutamylethylamide | ? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methyloversatilis universalis | D7R618 | gene gms | - |
| Methyloversatilis universalis FAM5 | D7R618 | gene gms | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially by ammonium sulfate fractionation | Methyloversatilis universalis |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.022 | 0.205 | different wild-type and mutant strains | Methyloversatilis universalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamic acid + ethylamine | - |
Methyloversatilis universalis | theanine | i.e. gamma-glutamylethylamide | ? | |
| L-glutamic acid + ethylamine | - |
Methyloversatilis universalis FAM5 | theanine | i.e. gamma-glutamylethylamide | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 48820, sequence calcualtion | Methyloversatilis universalis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gamma-Glutamylmethylamide synthetase | - |
Methyloversatilis universalis |
| GMAS | - |
Methyloversatilis universalis |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Methyloversatilis universalis | gamma-glutamylmethylamide synthetase is induced during growth on methylated amines | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | GMAS is involved in the gamma-glutamylmethylamine methylamine utilization pathway | Methyloversatilis universalis |
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Release 2023.1 (January 2023)
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