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Literature summary for 6.3.3.1 extracted from

  • Fluri, R.; Coddington, A.; Flury, U.
    The product of the ade1 gene in Schizosaccharomyces pombe: a bifunctional enzyme catalysing two distinct steps in purine biosynthesis (1976), Mol. Gen. Genet., 147, 271-282.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
4-6 * 40000, SDS-PAGE, bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity. Phosphoribosyl-glycinamide synthetase activity is associated with both the monomeric and multimeric forms, but AIR synthetase is only associated with the multimer Schizosaccharomyces pombe
240000
-
gel filtration, bifunctional enzyme with AIR synthetase activity and phosphoribosylglycinamide synthetase activity Schizosaccharomyces pombe

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity
-

Purification (Commentary)

Purification (Comment) Organism
bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity Schizosaccharomyces pombe

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine
-
Schizosaccharomyces pombe ADP + phosphate + 1-(5-phosphoribosyl)-5-aminoimidazole
-
?

Subunits

Subunits Comment Organism
? 4-6 * 40000, SDS-PAGE, bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity. Phosphoribosyl-glycinamide synthetase activity is associated with both the monomeric and multimeric forms, but AIR synthetase is only associated with the multimer Schizosaccharomyces pombe