Literature summary for 6.3.2.7 extracted from

Mengin-Lecreulx, D.; Falla, T.; Blanot, D.; van Heijenoort, J.; Adams, D.J.; Chopra, I.
Expression of the Staphylococcus aureus UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine ligase in Escherichia coli and effects on peptidoglycan biosynthesis and cell growth (1999), J. Bacteriol., 181, 5909-5914.

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Activating Compound

Activating Compound	Comment	Organism	Structure
isopropyl-beta-D-thiogalactosylpyranoside	concentration 1mM	Staphylococcus aureus

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli. Overexpression induced with isopropyl-beta-D-thiogalactosylpyranoside results in abnormal morphological changes and subsequent cell lysis	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.07	-	noninduced cells	Staphylococcus aureus
23.4	-	cells induced with isopropyl-beta-D-thiogalactosylpyranoside	Staphylococcus aureus

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Release 2023.1 (January 2023)