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Literature summary for 6.3.2.7 extracted from

  • Ito, E.; Strominger, J.L.
    Enzymatic synthesis of the peptide in bacterial uridine nucleotides. I. Enzymatic addition of L-alanine, D-glutamic acid, and L-lysine (1962), J. Biol. Chem., 237, 2689-2695.
No PubMed abstract available
Search for more literature for 6.3.2.7

Inhibitors

Inhibitors Comment Organism Structure
ATP above 10 mM Staphylococcus aureus
UDP-N-acetylmuramoyl-L-Ala-D-Glu above 10 mM Staphylococcus aureus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Mg2+ or Mn2+ required Staphylococcus aureus
Mg2+ optimal concentration: 30 mM Staphylococcus aureus
Mn2+ Mn2+ or Mg2+ required, optimal concentration: 2 mM Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
 temperature sensitive mutant
-

Purification (Commentary)

Purification (Comment) Organism
-
 Staphylococcus aureus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu + L-Lys
-
 Staphylococcus aureus ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys
-
 ?
ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu + L-Lys
-
 Staphylococcus aureus Copenhagen ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5 9
-
 Staphylococcus aureus