Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
bifunctional enzyme with phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase activities | - |
General Information | Comment | Organism |
---|---|---|
physiological function | Zygotic paics mutants have pigmentation defects in which xanthophore and iridophore pigmentation is almost completely absent, and melanin-derived pigmentation is significantly decreased, even though pigment cells are present in normal amounts and distributions. Zygotic paics mutants are also microphthalmic, resulting from defects in cell cycle exit of proliferative retinoblasts within the developing eye. Maternal-zygotic and maternal-effect mutants demonstrate a crucial requirement for maternally derived paics, these mutants show more severe developmental defects than their zygotic counterparts | Danio rerio |