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Literature summary for 6.3.2.5 extracted from

  • Manoj, N.; Strauss, E.; Begley, T.P.; Ealick, S.E.
    Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution (2003), Structure, 11, 927-936.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine ping pong mechanism Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-4'-phosphopantothenate + L-Cys
-
Homo sapiens (R)-4'-phosphopantothenoyl-L-cysteine + ADP + phosphate
-
?

Subunits

Subunits Comment Organism
dimer two identical subunits, crystallization data Homo sapiens