Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[[(4-fluorophenyl)sulfonyl]amino]-3-(morpholin-4-yl)propan-2-yl dihydrogen phosphate | 0.5 mM, 75% inhibition | Enterococcus faecium | |
1-[[(4-fluorophenyl)sulfonyl]amino]-3-(morpholin-4-yl)propan-2-yl dihydrogen phosphate | 0.5 mM, 77% inhibition | Escherichia coli | |
1-[[(4-fluorophenyl)sulfonyl]amino]-3-(morpholin-4-yl)propan-2-yl phenyl hydrogen phosphate | 0.5 mM, 65% inhibition | Enterococcus faecium | |
1-[[(4-methoxyphenyl)sulfonyl]amino]-3-(morpholin-4-yl)propan-2-yl dihydrogen phosphate | 0.5 mM, 83% inhibition | Enterococcus faecium | |
1-[[(4-methoxyphenyl)sulfonyl]amino]-3-(morpholin-4-yl)propan-2-yl dihydrogen phosphate | 0.5 mM, 83% inhibition | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecium | - |
isoform VanA | - |
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2 D-Ala | - |
Escherichia coli | ADP + phosphate + D-Ala-D-Ala | - |
? | |
ATP + 2 D-Ala | - |
Enterococcus faecium | ADP + phosphate + D-Ala-D-Ala | - |
? | |
ATP + D-Ala + D-lactate | enzyme uses both D-Ala and D-lactate as a substrate | Enterococcus faecium | ADP + phosphate + D-Ala-D-lactate | - |
? |