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Literature summary for 6.3.2.3 extracted from

  • Meister, A.
    Glutathione synthetase from rat kidney (1985), Methods Enzymol., 113, 393-399.
    View publication on PubMed
Search for more literature for 6.3.2.3

Inhibitors

Inhibitors Comment Organism Structure
PCMB
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.033
-
 ATP
-
 Rattus norvegicus
0.76
-
 Gly
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
K+ strict requirement for monovalent cation, maximal activity with K+ Rattus norvegicus
Li+ can replace K+ Rattus norvegicus
NH4+ can replace K+ Rattus norvegicus
Rb+ can replace K+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
13.75
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + beta-aminoglutaryl-L-2-aminobutyrate + Gly
-
 Rattus norvegicus ADP + phosphate + beta-aminoglutaryl-L-2-aminobutyryl-Gly
-
 ?
ATP + gamma-Glu-aminobutyrate + Gly D-gamma-Glu-L-2-aminobutyrate Rattus norvegicus ADP + phosphate + ophthalmic acid
-
 ?
ATP + gamma-Glu-L-Cys + Ala
-
 Rattus norvegicus ADP + phosphate + gamma-Glu-Cys-Ala
-
 ?
ATP + gamma-Glu-L-Cys + Gly
-
 Rattus norvegicus ADP + phosphate + glutathione
-
 ?
ATP + gamma-Glu-L-Cys + Ser
-
 Rattus norvegicus ADP + phosphate + gamma-Glu-Cys-Ser
-
 ?
dATP + gamma-Glu-L-Cys + Gly
-
 Rattus norvegicus dADP + phosphate + glutathione
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 8.5
-
 Rattus norvegicus