Application | Comment | Organism |
---|---|---|
medicine | gamma-GCS gene is the downstream target of c-Myc oncoprotein, driving the response to ROS-inducing drugs. gamma-GCS impairment might specifically sensitize high c-Myc tumor cells to chemotherapy | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
generation of C57Bl/6 mice that conditionally overexpress glutamate-cysteine ligase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
melanoma cell | gamma-glutamylcysteine synthetase mediates the c-Myc-dependent response to antineoplastic agents in melanoma cells | Homo sapiens | - |