Literature summary for 6.3.2.17 extracted from

Kimlova, L.J.; Pyne, C.; Keshavjee, K.; Huy, J.; Beebakhee, G.; Bognar, A.L.
Mutagenesis of the folC gene encoding folylpolyglutamate synthetase-dihydrofolate synthetase in Escherichia coli (1991), Arch. Biochem. Biophys., 284, 9-16.

Search for more literature for 6.3.2.17

Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
additional information	the enzyme cloned in a pUc19 vector is mutagenized by progressive deletion from both the 5'-end and the 3ïend and by TAB linker insertion. The specific activities of the extracts of the mutant enzyme are 4-16% that of the wild type enzyme. Non of the carboxy terminal or linker insertion mutants has a specific activity greater than 0.5% that of the wild type enzyme	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme also posseses dihydrofolate synthetase activity	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)