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Literature summary for 6.3.2.12 extracted from
- Dihydrofolate synthetase (1971), Methods Enzymol., 18B, 771-775.
No PubMed abstract available
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| K+ | monovalent cation requirement is satisfied by K+ or NH4+ | Escherichia coli |  |
| Mg2+ | required | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 7,8-dihydropteroate + L-Glu | - |
Escherichia coli | ADP + phosphate + 7,8-dihydrofolate | - |
? | |
| GTP + 7,8-dihydropteroate + L-Glu | 35% of the activity relative to ATP | Escherichia coli | GDP + phosphate + 7,8-dihydrofolate | - |
? | |
| ITP + 7,8-dihydropteroate + L-Glu | at 60% of the activity relative to ATP | Escherichia coli | IDP + phosphate + 7,8-dihydrofolate | - |
? | |
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Release 2023.1 (January 2023)
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