Crystallization (Comment) | Organism |
---|---|
crystal structures with compounds 5-methoxyindole and 2-carboxybenzofuranoic acid bound in a ternary complex and in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-benzofuran-2-carboxylic acid | competitive with respect to both ATP and pantoate | Mycobacterium tuberculosis | |
2-methyl-5-methoxyindole | binding mode with the 2-CH3 group facing the pantoate pocket | Mycobacterium tuberculosis | |
5-methoxyindole | competitive with respect to ATP | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WIL5 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WIL5 | - |
- |