Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2RS)-5'-O-(2-hydroxy-4-methoxybutyrylsulfamoyl)adenosine | - |
Escherichia coli | |
(2RS)-5'-O-(3,3-dimethyl-2-aminobutyrylsulfamoyl)adenosine | - |
Escherichia coli | |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxy-4-methoxybutyrylsulfamoyl)adenosine | - |
Escherichia coli | |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxybutyrylsulfamoyl)adenosine | - |
Escherichia coli | |
(2RS)-5'-O-(3,3-dimethyl-2-oxobutyrylsulfamoyl)adenosine | - |
Escherichia coli | |
(2RS)-adenosyl-2-hydroxy-3,3-dimethylbuyrate | - |
Escherichia coli | |
(2RS)-adenosyl-2-hydroxy-4-methoxybutyrate | - |
Escherichia coli | |
(2RS)-adenosyl-3,3-dimethyl-2-hydroxy-4-methoxybutyrate | - |
Escherichia coli | |
(2S)-adenosyl-2-L-amino-3,3-dimethylbutanoate | - |
Escherichia coli | |
3,3-dimethyl-2-oxobutyric acid 5-(6-aminopurin-9-yl)-3,4-dihydroxytetrahydrofuran-2-ylmethyl ester | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.31 | - |
beta-Alanine | 25°C | Escherichia coli | |
1.45 | - |
(R)-pantoate | 25°C | Escherichia coli | |
1.75 | - |
ATP | 25°C | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P31663 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-pantoate + beta-alanine | - |
Escherichia coli | AMP + diphosphate + (R)-pantothenate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.4 | - |
ATP | 25°C | Escherichia coli | |
1.4 | - |
beta-Alanine | 25°C | Escherichia coli | |
1.4 | - |
(R)-pantoate | 25°C | Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0003 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.0008 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.0008 | - |
(2RS)-5'-O-(2-hydroxy-4-methoxybutyrylsulfamoyl) adenosine | 25°C | Escherichia coli | |
0.0011 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.014 | - |
(2RS)-5'-O-(3,3-dimethyl-2-oxobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.015 | - |
(2RS)-5'-O-(3,3-dimethyl-2-oxobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.03 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxy-4-methoxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.054 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxy-4-methoxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.065 | - |
(2RS)-5'-O-(3,3-dimethyl-2-aminobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.12 | - |
(2RS)-5'-O-(3,3-dimethyl-2-oxobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.144 | - |
(2RS)-5'-O-(3,3-dimethyl-2-hydroxy-4-methoxybutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.16 | - |
(2RS)-5'-O-(3,3-dimethyl-2-aminobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
0.25 | - |
(2RS)-5'-O-(3,3-dimethyl-2-aminobutyrylsulfamoyl)adenosine | 25°C | Escherichia coli | |
1.9 | - |
3,3-dimethyl-2-oxobutyric acid 5-(6-aminopurin-9-yl)-3,4-dihydroxytetrahydrofuran-2-ylmethyl ester | 25°C | Escherichia coli | |
2.5 | - |
(2RS)-adenosyl-2-hydroxy-3,3-dimethylbuyrate | 25°C | Escherichia coli | |
3.5 | - |
(2RS)-adenosyl-2-hydroxy-4-methoxybutyrate | 25°C | Escherichia coli | |
9.5 | - |
(2S)-adenosyl-2-L-amino-3,3-dimethylbutanoate | 25°C | Escherichia coli | |
18.2 | - |
(2RS)-adenosyl-3,3-dimethyl-2-hydroxy-4-methoxybutyrate | 25°C | Escherichia coli |