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Literature summary for 6.3.1.20 extracted from

  • Morris, T.W.; Reed, K.E.; Cronan, J.E., Jr.
    Lipoic acid metabolism in Escherichia coli: the lplA and lipB genes define redundant pathways for ligation of lipoyl groups to apoprotein (1995), J. Bacteriol., 177, 1-10.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
G76S substitution in LplA ligase gene, is identical to slr1 selenolipoate restistance mutation Escherichia coli
additional information lplA null mutants display no growth defect unless combined with lipA or lipB lipoate synthesis mutations Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli LipB protein utilizes lipoyl groups generated via endogenous, LipA mediated biosynthesis and causes the accumulation of aberrantly modified octanoyl-proteins in lipoate-deficient cells ?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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isoenzymes LplA and LipB
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information LipB protein utilizes lipoyl groups generated via endogenous, LipA mediated biosynthesis and causes the accumulation of aberrantly modified octanoyl-proteins in lipoate-deficient cells Escherichia coli ?
-
?