Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.2.1.7 extracted from

  • ึstlund, A.K.; Nilsson, A.; Pedersen, J.I.
    Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation (1993), J. Lipid Res., 34, 2041-2050.
    View publication on PubMed
Search for more literature for 6.2.1.7

Inhibitors

Inhibitors Comment Organism Structure
palmitate concempetitive, potent Rattus norvegicus

Organism

Organism UniProt Comment Textmining
no activity in Homo sapiens
-
 no activity detected in HepG2 hepatoblastoma cells
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information no activity in 7800 C1 Morris hepatoma cells Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate + CoA
-
 Rattus norvegicus AMP + diphosphate + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA
-
 ?