Literature summary for 6.2.1.4 extracted from

Baccanari, D.P.; Cha, S.
Succinate thiokinase. VI. Multiple interconvertible forms of the enzyme (1973), J. Biol. Chem., 248, 15-24.

Search for more literature for 6.2.1.4

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.004	-	CoA	enzyme form pI 6.4	Sus scrofa
0.005	-	CoA	enzyme form pI 5.8	Sus scrofa
0.006	-	CoA	enzyme forms pI 6.2 and pI 6.0	Sus scrofa
0.007	-	CoA	enzyme form pI 5.9	Sus scrofa
0.009	-	GTP	enzyme form pI 6.4	Sus scrofa
0.01	-	GTP	enzyme form 6.0	Sus scrofa
0.011	-	GTP	enzyme forms pI 6.2, pI 5.9 and pI 5.8	Sus scrofa
0.39	-	succinate	enzyme form pI 6.4	Sus scrofa
0.43	-	succinate	enzyme forms pI 5.9 and pI 5.8	Sus scrofa
0.45	-	succinate	enzyme form pI 6.0	Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
74000	-	enzyme pI 6.0, at pI, gel filtration	Sus scrofa
77000	-	enzyme form pI 5.9, at pH 8.0, gel filtration	Sus scrofa
78000	-	enzyme form pI 6.3, at pH 8.0 and at pI, gel filtration	Sus scrofa
79250	-	enzyme form pI 6.0, at pH 8.0, gel filtration	Sus scrofa
80000	-	enzyme form pI 6.4, at pI, gel filtration	Sus scrofa
82500	-	enzyme form pI 6.4, at pH 8.0, gel filtration	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
at least 5 peaks of enzyme having isoelectric points of 6.4, 6.2, 6.0, 5.9 and 5.8	Sus scrofa

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Sus scrofa	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	-	Sus scrofa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + succinate + CoA	-	Sus scrofa	GDP + phosphate + succinyl-CoA	-	?

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Release 2023.1 (January 2023)