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Literature summary for 6.2.1.3 extracted from

  • Pulsifer, I.P.; Kluge, S.; Rowland, O.
    Arabidopsis long-chain acyl-CoA synthetase 1 (LACS1), LACS2, and LACS3 facilitate fatty acid uptake in yeast (2012), Plant Physiol. Biochem., 51, 31-39.
    View publication on PubMed
Search for more literature for 6.2.1.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in a yeast fat1DELTA mutant which is deficient in both very-long-chain acyl-CoA synthetase activity and exogenous fatty acid uptake Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Bodipy-C16 + CoA
-
 Arabidopsis thaliana ?
-
 ?
ATP + C1-Bodipy-C12 + CoA
-
 Arabidopsis thaliana ?
-
 ?
additional information Arabidopsis isoforms LACS1-3 display broad substrate specificities, ranging from saturated and monounsaturated C16, C18 and C20 fatty acids to saturated very-long-chain fatty acids Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
FATP
-
 Arabidopsis thaliana
fatty acid transport protein
-
 Arabidopsis thaliana
LACS1 isoform Arabidopsis thaliana
LACS2 isoform Arabidopsis thaliana
LACS3 isoform Arabidopsis thaliana
long-chain acyl-CoA synthetase
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function Arabidopsis long-chain acyl-CoA synthetase isoforms LACS1, LACS2, and LACS3 facilitate fatty acid uptake in yeast. Expression of each isoform in yeast results in uptake of the long-chain fatty acid analogue, C1-Bodipy-C12. Only expression of LACS1 results in uptake of the very-long-chain fatty acid analogue, Bodipy-C16 Arabidopsis thaliana