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Literature summary for 6.1.2.1 extracted from

  • Bisicchia, P.; Bui, N.K.; Aldridge, C.; Vollmer, W.; Devine, K.M.
    Acquisition of VanB-type vancomycin resistance by Bacillus subtilis: the impact on gene expression, cell wall composition and morphology (2011), Mol. Microbiol., 81, 157-178.
    View publication on PubMed
Search for more literature for 6.1.2.1

Cloned(Commentary)

Cloned (Comment) Organism
gene vanA, the gene is located on a polycistronic van operon Bacillus subtilis

Protein Variants

Protein Variants Comment Organism
additional information construction of several mutant strains, generating a Bacillus subtilis strain BP341A expressing a depsipeptide-containing (D-Ala-D-Lac) lipid II, phenotype, overview. Strains BP341A-E, that require expression of the VanB-type operon for growth, have mutations in the endogenous Ddl ligase Bacillus subtilis

Inhibitors

Inhibitors Comment Organism Structure
Vancomycin
-
 Bacillus subtilis

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
 gene vanA
-
Bacillus subtilis 168
-
 gene vanA
-

Synonyms

Synonyms Comment Organism
D-Ala-D-Lac ligase
-
 Bacillus subtilis
VanA
-
 Bacillus subtilis

General Information

General Information Comment Organism
additional information acquisition of vancomycin resistance affects expression of WalRK and PhoPR regulon genes in the phosphate-limited state. Genetic regulation of vancomycin resistance involving also VanA, detailed overview Bacillus subtilis