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Literature summary for 6.1.1.9 extracted from
- Affinity labeling of aminoacyl-tRNA synthetases with adenosine triphosphopyridoxal. Probing the Lys-Met-Ser-Lys-Ser signature sequence as the ATP-binding site in Escherichia coli methionyl- and valyl-tRNA synthetases (1990), Biochemistry, 29, 11266-11273.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-triphospho-5'-adenosine | aminoacylation and ATP-diphosphate exchange abolished | Escherichia coli |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-valine + tRNAVal | - |
Escherichia coli | AMP + diphosphate + L-valyl-tRNAVal | - |
? | |
| additional information | valine-dependent ATP-diphosphate exchange: valine + ATP + enzyme /Val-AMP-enzyme + diphosphate | Escherichia coli | ? | - |
? | |
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Release 2023.1 (January 2023)
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