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Literature summary for 6.1.1.6 extracted from

  • Guzzo, C.M.; Yang, D.C.
    Lysyl-tRNA synthetase interacts with EF1alpha, aspartyl-tRNA synthetase and p38 in vitro (2008), Biochem. Biophys. Res. Commun., 365, 718-723.
    View publication on PubMed
Search for more literature for 6.1.1.6

Activating Compound

Activating Compound Comment Organism Structure
aspartyl-tRNA synthetase EC 6.1.1.12, AspRS, from the multi-synthetase complex. HKRS and hKRSDELTA60 are differentially stimulated by Homo sapiens
additional information the non-synthetase protein from the multi-synthetase complex p38 alone does not affect hKRS lysylation but inhibited the AspRS-mediated stimulation of hKRS Homo sapiens
translation elongation factor 1alpha EF1alpha, hKRSDELTA60 binds to EF1alpha and is stimulated by EF1alpha in vitro Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Protein Variants

Protein Variants Comment Organism
hKRSDELTA1-24 deletion mutation. Construct shows significant stimulation of lysylation by EF1alpha and binding to EF1alpha Homo sapiens
hKRSDELTA24-42 deletion mutation. Construct shows significant stimulation of lysylation by EF1alpha and binding to EF1alpha Homo sapiens
hKRSDELTA60 removal of the amino-terminal extension Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q15046
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
hKRS
-
 Homo sapiens
Lysyl-tRNA synthetase interacts with EF1alpha, aspartyl-tRNA synthetase (EC 6.1.1.12) and p38 in vitro Homo sapiens